1.
Mem. Inst. Oswaldo Cruz
;
104(5): 703-705, Aug. 2009. ilus, tab
Article
in English
| LILACS
| ID: lil-528076
ABSTRACT
A series of diamines and amino alcohols derived from 1-dodecanol, 1-tetradecanol, 1,2-dodecanediol and 1,2-tetradecanediol were synthesized and tested for their antitubercular activity. Compounds 3, 8 and 9 were found to be the most active (MIC of 6.25 µg/mL). Nine other compounds displayed activity against Mycobacterium tuberculosis, with a MIC of 12.5 µg/mL.